Metropolis healthcare’s study Reveals key insights in Prenatal Testing to detect high-risk pregnancies

Aims to empower expecting couples with essential knowledge and awareness regarding their baby’s health

Metropolis Healthcare, aimed to empower expecting couples with essential knowledge and awareness regarding their baby’s health, has revealed a three-year study (January 2021 to December 2023) involving 140,528 pregnant women.

It released findings in prenatal care through Pregascreen Reflex Testing in conjunction with Non-invasive Prenatal Testing (NIPT) or Karyotyping. This study was aimed to assess the impact of Reflex Testing for detecting fetal abnormalities.

The study revealed that out of 140,528 pregnancies, 5,879 were initially identified as high-risk through traditional early trimester screenings. By integrating NIPT with Pregascreen reflex testing, the accuracy of identifying true high-risk cases improved significantly.

In the first trimester, dual marker testing initially indicated 2,416 cases as high-risk.

However, after NIPT reflex testing, only 64 of these remained classified as high-risk, accurately identifying 1,142 cases as low risk. Similarly, in the second trimester, among 3,463 cases flagged by the Quadruple marker, NIPT correctly reassigned 455 cases as low risk, with only 20 still considered high-risk.

These findings highlight the significant impact of NIPT and Pregascreen reflex testing in improving the precision of prenatal screening. By reducing false positives and accurately identifying genuine high-risk pregnancies, this integrated approach allows for more focused and effective prenatal care, ultimately improving maternal and fetal health outcomes.

Overall, Pregascreen reflex testing with NIPT offers several advantages. It enhances diagnostic accuracy, is non-invasive, and thus, eliminates the risks associated with invasive procedures.  It increases the accessibility of advanced prenatal diagnostics to a broader range of expectant couples.

Looking forward, Metropolis Healthcare is committed to expanding its services and integrating the latest technologies to reduce the burden of maternal health and improve access to innovative healthcare solutions.