Immunoturbidimetry reagents: Highest performance in protein testing

Sachin Singh, Head: Strategic & Operational Marketing, DiaSys Diagnostic India, gives an insight on the characteristics of immunoturbidimetric assays, which have resulted in more reliable protein tests and reduced laboratory variances to help clinicians

The growing need of IVD testing arises due to increasing incidences of chronic and infectious diseases and growing geriatric population prone to immunological disorders. Moreover, increased application of personalised medicines and widespread knowledge of rare diseases are boosting the growth of IVD market. Another such rise has been observed in testing specific proteins for infectious diseases, cardiac diseases, diabetes, autoimmune disorders, inflammatory markers and others.

Immunoturbidimetric methods have become the main technique for performing specific protein tests. The transition from nephelometry has been cautious but is increasing as laboratories enjoy the comparability and flexibility of immunoturbidimetry. Immunoturbidimetric and nephelometric techniques measures turbidity of a sample to determine the level of analyses. It is also observed that specific proteins have traditionally been analysed using methodologies, such as immunonephelometry on specialised analysers. Although, immunonephelometry is a well-recognised and accepted methodology, it requires a specialised analyser that performs a limited menu of tests. In addition, nephalometers are slow with expensive consumables cost and requires trained and experienced person to run the assay.

A variety of immunoturbidimetric assays are now available, and can be adapted to general purpose clinical chemistry analysers that are ‘Open Systems.’ Immunoturbidimetric assays have been improved considerably over time. These improvements include advances in antibody purification techniques, enhancements in instrument design, function and production of new reference materials based on global standardisation initiatives. Additional practical advantages of immunoturbidimetric protein assays include random access analysis instead of batch testing, relatively rapid turnaround time, high volume testing capability, cost reduction through consolidation of testing on a single platform, elimination of stand alone specialised analysers, and time and effort required to maintain them. Collectively, these characteristics of immunoturbidimetric assays have resulted in more reliable tests and reduced laboratory variances to help the clinicians.

DiaSys Diagnostic Systems immunoturbidimetric test portfolio offers more than 20 ready-to-use, stability optimised reagents for routine and special diagnostics with outstanding performance. DiaSys immunoturbidimetric tests are available in different vials and kit sizes for manual and automated use in various common clinical chemistry analysers. DiaSys reagents, in combination with DiaSys instruments, optimised applications, calibrators and quality control material form a harmonised system for highest laboratory demands.

Salient features

• Liquid-stable, ready-to-use reagents
• Widest measuring ranges. No sample pre-dilution
• High prozone security
• Minimised interferences. Advanced lipid clearing system
• Excellent on board stability
• Extended calibration stability
• Standardised to international reference material or reference methods
• Applications available for a variety of common automated systems

Current portfolio of DiaSys Immunoturbidimetry tests available as open kits and system kits on respons 910- Dedicated Immunoturbidimetry analyser

Contact Details:
DiaSys Diagnostics India
Unit no. 3B/33, 34,
3rd Floor, Phoenix Paragons
Plaza, Kurla West,
Mumbai – 400 070.
Tel: +91 (022) 3371 4300
Email: info@diasys.in