Dr Mangesh Kamath, Senior consultant Medical Oncologist, Hematology, BMT Physician, Bhagwan Mahaveer Jain hospitals and Healius Cancer & Hematology Clinics, Bangalore talks about pioneering innovations in breast cancer screening
The world is witnessing significant strides in the fight against breast cancer, a testament to the resilience and courage displayed by countless individuals throughout their challenging journey. At the core of this struggle resides a fundamental hope: early detection. With a staggering 500,000 global deaths and 75,000 in India annually, prompt diagnosis becomes the critical prerequisite for ensuring positive outcomes. [1]
In recent years, innovations in breast cancer care to improve early detection, diagnosis, treatment, and survival have advanced significantly. This progress is evident in the rapid development of breast imaging and localisation methods, the integration of genetic and genomic profiling for personalised medicine, the emergence of implantable devices, as well as the seamless integration of artificial intelligence and deep learning models. These advancements collectively empower healthcare professionals to provide more precise and tailored interventions, ultimately leading to improved outcomes for patients.[2]
Pioneering innovations in breast cancer screening
While breast cancer screening has made significant progress, challenges persist. While mammography, clinical breast exams, and self-exams have been the primary tools, they possess limitations. They may miss subtle signs or trigger unwarranted alarms, necessitating more refined approaches. 3D Mamographs or digital breast tomosynthesis (DBT) provides meticulously detailed imaging and has redefined early detection standards by enhancing our ability to detect the most minuscule abnormalities at the earliest and most manageable stages. It is a more accurate and cost-effective alternative to breast MRI, albeit with a higher radiation dosage.[3]
Personalised approaches to screening
One size doesn’t fit all, especially in breast cancer screening. Personalised medicine has emerged as a transformative approach. Genetic testing and risk assessment tools now allow us to tailor screening plans based on an individual’s unique genetic makeup and risk factors. This precision minimises unnecessary procedures and ensures that each patient receives the care they specifically require.
Revolutionising early detection
Liquid biopsy and thermal imaging champion early detection by offering non-invasive methods to detect cancer-related genetic mutations, fundamentally transforming our diagnostic capabilities. Meanwhile, thermal imaging detects subtle temperature variations indicative of early-stage tumors. These breakthroughs promise to unlock new dimensions in our battle against breast cancer. The essence of innovation diminishes when it remains out of reach for those who require it the most. Financial limitations, geographical disparities, and insufficient awareness create formidable obstacles. However, through various public and private initiatives, education and awareness outreach, we can ensure better access and adoption of these technologies for early detection.
In conclusion, early detection is not just an aspiration; it’s an imperative. The innovations in breast cancer screening and detection are the heralds of a new era in care. By championing accessibility and overcoming the inhibitions, we can aspire for a future where breast cancer is met with early intervention and higher survival rates. Together, we can break barriers, redefine standards, and ultimately triumph over breast cancer.
References
[1] Expanding the horizon for breast cancer screening in India through artificial intelligent technologies -A mini-review – PMC (nih.gov)
[2] Innovations and Challenges in Breast Cancer Care: A Review – PMC (nih.gov)
[3] Digital Breast Tomosynthesis: Potential Benefits in Routine Clinical Practice – PubMed (nih.gov)
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